Vibhuti Agrahari, Ph.D.

Assistant Professor

Pharmaceutical Sciences

Phone 405-271-6751 x47244

Fax 405-271-7505

Office CPB 325

Email vibhuti-agrahari@ouhsc.edu


Summary

My research focuses on long-term drug delivery by designing innovative systems such as nanocarriers, micelles, and hydrogels using biomaterials. The research activities include rationale design, optimization, and evaluation of the nanoformulations for local, targeted and sustained delivery of biotherapeutic and small molecule drugs using stimuli-responsive polymers, natural polymers, block- and random- copolymers, etc. The ultimate goal of my research laboratory is to develop biomaterials that can provide selective, controlled, non-toxic, biodegradable, and stimuli-responsive platforms to target therapeutic agents to the sites of ocular and inner ear diseases. My laboratory is specialized in the area of (a) sustained delivery of protein/antibodies for the back of eye diseases. (b) non-invasive treatment, and prevention of vision loss due to ocular injuries. (c) next-generation therapeutics for anterior segment ocular diseases (d) nanotherapeutic approaches to provide a prophylactic cure for Chemotherapeutic-Induced Ototoxicity (CIO). 




Grants

New Investigator Grant: "Bio-responsive NanoSensoGel for Prevention of Cisplatin-induced Ototoxity and Hearing Loss"

Presbyterian Health Foundation

07/01/2021 - 06/30/2022

CFAR Grant: "ROS-responsive NanoSensoGel for Prevention of Cistplatin-Induced Ototoxicity and Hearing Loss"

Capita Foundation

11/01/2021 - 12/31/2022


Publications & Presentations

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    36. Joseph M, Patel S P, Agrahari V, Mitra A K. Pentablock Copolymer nano formulation for controlled Ocular Delivery of Protein Therapeutics. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2014; 55

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Grants

    1. Bio-responsive Nano-SensoGel for Prevention of Chemotherapy-Induced Ototoxicity and Hearing Loss . Non-federal. Start Date: 2021. End Date: 2022.




Awards and Honors

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                                                                                            6. National Biotechnology Conference, AAPS. Biotechnology Graduate Student Symposium Award,. Date: 2016.  

                                                                                            7. University of Missouri-Kansas City Preparing Future Faculty Program Scholar Award. Date: 2016.  

                                                                                            8. American Association of Pharmaceutical Scientists. Quality by Design and Product Performance Graduate Student Award. Date: 2016.  

                                                                                            9. University of Missouri-Kansas City Ronald MacQuarrie Fellowship. Date: 2016.  

                                                                                            10. University of Missouri System. Graduate Student Professional Development and Leadership Program. Date: 2015.  

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Education

                                                                                            1.  Degree: Ph D. University of Missouri- Kansas City. Date: 2017.  

                                                                                            2.  Degree: M. Pharm.. Shri G.S. Institute of Technology & Science, India . Date: 2008.  

                                                                                            3.  Degree: B. Pharm. Shri G.S. Institute of Technology & Science, India . Date: 2005.  




Administrative Assignments


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