Vibhudutta Awasthi, Ph.D.

Prof

Pharmaceutical Sciences

Phone (405) 271-6593 x47331

Fax (405) -271-7505

Office COP200

Email Vibhudutta-Awasthi@ou.edu


Summary

My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.



Publications & Presentations

    56. Yadav V, Vilekar P, Awasthi S, Awasthi V. Hemorrhage-induced IL-1R pathway in lung is suppressed by EF24, a synthetic curcuminoid, in a rat model of hypovolemic shock. Artif Organs. 2014; 38 : 675-683

    57. Awwad H O, Simpson-Durand C D, Gonzalez L P, Tompkins P, Zhang Y, Lerner M, Brackett D J, Sherry D M, Awasthi V, Standifer K. Post-blast treatment with Nociceptin/Orphanin FQ peptide receptor antagonist reduces traumatic brain injury-induced cerebral hypoxia. Neuroscience 2014 program and website. 2014

    58. Yadav V R, Hussain A, Kaustuv S, Awasthi V. Remediation of hemorrhagic shock-induced intestinal barrier dysfunction by treatment with diphenyldihaloketones EF24 and CLEFMA. J Pharmacol Exp Ther. 2014; 351 : 413-422

    59. Yadav V, Sahoo K, Awasthi V. Pre-clinical evaluation of CLEFMA, 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid in a mouse model of lung cancer xenograft. Br J Pharmacol. 2013; 170 : 1436–1448

    60. Awasthi V, Nag O. Surface engineering of liposomes for stealth behavior. Pharmaceutics. 2013; 5 : 542-569




Grants

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    11. Development of Tumor Proliferation PET Tracer FLT using a Low Cost Single Dose Automatic Production and Quality Control Biomarker Generator System. NIH. Start Date: 2016. End Date: 2017.

    12. Molecular mechanisms of chronic pain and its modulation by posttraumatic stress disorder and Nociceptin/Orphanin FQ. DOD. Start Date: 2011. End Date: 2015.

    13. FDG Synthesis Optimization. Non-federal. End Date: 2014.

    14. Evaluation of freeze-dried platelets in a rabbit model . Non-federal. Start Date: 2007. End Date: 2010.

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Awards and Honors

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                                                                                            1. USPTO. Patent application issued. Date: 2015.  

                                                                                            2. Indo-American Society of Nuclear Medicine (IASNM)Outstanding Presidential Award . Date: 2015.  

                                                                                            3. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.  

                                                                                            4. OUHSC-College of Pharmacy. USP Convention Voting Delegate. Date: 2014.  

                                                                                            5. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.  

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Education

                                                                                            1.  Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.  

                                                                                            2.  Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.  

                                                                                            3.  Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.  




Administrative Assignments

                                                

    1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.

                                                

    2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.




External Connections and Partnerships


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