Vibhudutta Awasthi, Ph.D.

Professor and Associate Dean for Research

Pharmaceutical Sciences

Phone (405) 271-6593 x47331

Fax (405) -271-7505

Office CPB 309

Email vibhudutta-awasthi@ouhsc.edu


Summary


My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.



Publications & Presentations

    61. Vilekar P, King C, Lagisetty P, Awasthi V, Awasthi S. Antibacterial activity of synthetic curcumin derivatives: 3,5-bis(benzylidene)-4-piperidone (EF24) and EF24-dimer linked via diethylenetriaminepentacetic acid (EF2DTPA). Appl Biochem Biotech. 2014; 172 : 3363-73

    62. Yadav V, Sahoo K, Awasthi V. Pre-clinical evaluation of CLEFMA, 4-(3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid in a mouse model of lung cancer xenograft. Br J Pharmacol. 2013; 170 : 1436–1448

    63. Awasthi V, Nag O. Surface engineering of liposomes for stealth behavior. Pharmaceutics. 2013; 5 : 542-569

    64. Pathuri G, Hedrick A F, Awasthi V, Ihnat M, Gali H. Evaluation of 99mTc-probestin for imaging APN expressing tumors by SPECT. Bioorg Med Chem Lett. 2013; 23 : 5049-52

    65. Yadav V, Sahoo K, Awasthi V. Pharmacologic suppression of inflammation by a dipheyldifluoroketone, EF24, in a rat model of fixed-volume hemorrhage improves survival. J Pharmacol Exp Ther . 2013; 347 : 346-356




Grants

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    11. Development of Tumor Proliferation PET Tracer FLT using a Low Cost Single Dose Automatic Production and Quality Control Biomarker Generator System. NIH. Start Date: 2016. End Date: 2017.

    12. Molecular mechanisms of chronic pain and its modulation by posttraumatic stress disorder and Nociceptin/Orphanin FQ. DOD. Start Date: 2011. End Date: 2015.

    13. FDG Synthesis Optimization. Non-federal. End Date: 2014.

    14. Evaluation of freeze-dried platelets in a rabbit model . Non-federal. Start Date: 2007. End Date: 2010.

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Awards and Honors

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                                                                                            1. USPTO. Patent application issued. Date: 2015.  

                                                                                            2. Indo-American Society of Nuclear Medicine (IASNM)Outstanding Presidential Award . Date: 2015.  

                                                                                            3. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.  

                                                                                            4. OUHSC-College of Pharmacy. USP Convention Voting Delegate. Date: 2014.  

                                                                                            5. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.  

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Education

                                                                                            1.  Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.  

                                                                                            2.  Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.  

                                                                                            3.  Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.  




Administrative Assignments

                                                

    1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.

                                                

    2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.




External Connections and Partnerships


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