Vibhudutta Awasthi, Ph.D.

Professor and Associate Dean for Research

Pharmaceutical Sciences

Phone (405) 271-6593 x47331

Fax (405) -271-7505

Office CPB 309

Email vibhudutta-awasthi@ouhsc.edu


Summary


My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.



Publications & Presentations

    66. Aravindan S, Natarajan M, Awasthi V, Herman T S, Aravindan N. Novel synthetic monoketone transmute radiation-triggered NFκB-dependent TNFα cross-signaling feedback maintained NFκB and favors neuroblastoma regression. PLoS One. 2013; 8 : e72464

    67. Lagisetty P, Agashe H, Awasthi V. 2-[3,5-bis-(2-fluorobenzylidene)-4-piperidon-1-yl]-N-(4-fluorobenzyl)-acetamide and its evaluation as an anticancer agent. Journal of Chemistry. 2013

    68. Pathuri G, Hedrick A F, Awasthi V, Gali H. Single-step radiosynthesis and in vivo evaluation of a novel fluorine-18 labeled hippurate for use as a PET renal agent. Nucl Med Biol. 2012; 39 : 1195-201

    69. Pathuri G, Hedrick A F, Disch B C, Ihnat M, Awasthi V, Gali H. Synthesis and biodistribution studies of technetium-99m-labeled aminopeptidase N inhibitor conjugates. Bioorg Med Chem Lett. 2012; 22 : 4567-70

    70. Vilekar P, Awasthi S, Natarajan A, Anant S, Awasthi V. EF24 suppresses maturation and inflammatory response in dendritic cells. International immunology. 2012; 24 : 455-64




Grants

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    6. STTR Phase I: Cardiotropic Atorvastatin Liposomes for Myocardial Reperfusion Injury. NSF. Start Date: 2023. End Date: 2021.

    7. Pharmacotherapy of Traumatic Brain Injury Accompanied by Hemorrhagic Shock. NIH. Start Date: 2017. End Date: 2022.

    8. Development of Bioactive Peptides for the Inhibition of Neuroinflammation and Neurotoxicity Induced by Amyloid-beta. Non-federal. Start Date: 2020. End Date: 2021.

    9. Immunokinetics of superhydrophilic polymer-modified liposome encapsulated hemoglobin. Non-federal. Start Date: 2017. End Date: 2020.

    10. PET Imaging Agent For Myocardial Infarction. NIH. Start Date: 2019. End Date: 2019.

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Awards and Honors

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                                                                                            1. USPTO. Patent application issued. Date: 2015.  

                                                                                            2. Indo-American Society of Nuclear Medicine (IASNM)Outstanding Presidential Award . Date: 2015.  

                                                                                            3. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.  

                                                                                            4. OUHSC-College of Pharmacy. USP Convention Voting Delegate. Date: 2014.  

                                                                                            5. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.  

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Education

                                                                                            1.  Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.  

                                                                                            2.  Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.  

                                                                                            3.  Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.  




Administrative Assignments

                                                

    1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.

                                                

    2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.




External Connections and Partnerships


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