Shanjana Awasthi, Ph.D.
Summary
Research in my lab is focused on developing immunotherapeutics and vaccines by harnessing our body's natural host defense mechanisms. Our research efforts have been focused on developing TLR4-interacting surfactant protein-A-derived peptides and dendritic cell-based vaccine approaches. We are interested in investigating the mechanisms of action and efficacy of these approaches using structural, computational, physicochemical, and immunological tools and methods, and in vitro and in animal models of infection, inflammation and cancer.
Certifications & Licenses
Categorical certificate in Clinical Microbiology
UTHSCSA, TX
2006Publications & Presentations
- 76. S S, Prasad K N, Chamoli D, Ayyagari A. Antimicrobial susceptibility pattern & biotyping of Helicobacter pylori isolates from patients with peptic ulcer diseases. The Indian journal of medical research. 1995; 102 : 261-6
77. Ayyagari A, S S. Detection of H. pylori infection. The National medical journal of India. 1995; 8 : 245-6
78. Ayyagari A, Awasthi S S, Prasad K, Yacha S K, Naik S R. Metronidazole resistant Helicobacter pylori in India. Am J Gastroenterology. 1994; 89
79. Prasad K, Singhal S, Ayyagari A, S S. Association of Helicobacter pylori in patients with nonulcer dyspepsia. Indian Journal of Microbiology. 1991; 31 : 415-418
Grants
- 1. Surfactant protein-A regions as TLR4-immunomodulators. NIH. Start Date: 2017. End Date: 2023.
2. Molecular mechanism of action of TLR4-interacting SPA4 peptide in lung epithelial cell systems. Non-federal. Start Date: 2021. End Date: 2022.
3. Immunomodulation by a TLR4-interacting Surfactant protein-A peptide. Non-federal. Start Date: 2013. End Date: 2021.
4. Control of lung inflammation by a TLR4-interacting SP-A-derived peptide. NIH. Start Date: 2013. End Date: 2017.
5. Structure-function relation of a TLR4-interacting Surfactant protein-A-derived peptide. NIH. Start Date: 2013. End Date: 2014.
Awards and Honors
- 1. University of Oklahoma Health Sciences Center. Presbyterian Health Foundation Presidential Professorship. Date: 2023.
2. University of Oklahoma Health Sciences Center. Member of Educators for Excellence. Date: 2022.
3. University of Oklahoma Health Sciences Center. Presbyterian Health Foundation Presidential Professorship. Date: 2022.
4. NIH. Received appreciation for serving on review panels. Date: 2022.
5. University of Oklahoma Health Sciences Center. Presbyterian Health Foundation Presidential Professorship. Date: 2021.
Education
- 1. Degree: Post-Baccalaureate Categorical certificate in Clinical Microbiology. University of Texas Health Sciences Center at San Antonio. Date: 2006.
2. Degree: Ph D. Sanjay Gandhi Post Graduate Institute of Medical Sciences. Date: 1995.
3. Degree: Master of Science. Indian Institute of Technology (IIT). Date: 1990.
4. Degree: Bachelor of Science. MKP College, University of Garhwal. Date: 1988.
Administrative Assignments
no results
External Connections and Partnerships
- 1. Type: Funding. Org: Oklahoma State University (2013-2017). City: Stillwater. State: Oklahoma. NIH-supported COBRE program in Respiratory and Infectious Diseases. Date: 2013.
2. Type: Funding. Org: University of Oklahoma (2013-2014). City: Norman. State: Oklahoma. NIH-supported COBRE program in Structural Biology. Date: 2013.