Vibhuti Agrahari, Ph.D.

Assistant Professor

Pharmaceutical Sciences

Phone 405-271-6751 x47244

Fax 405-271-7505

Office CPB 325

Email vibhuti-agrahari@ouhsc.edu

Summary

My research focuses on long-term drug delivery by designing innovative systems such as nanocarriers, micelles, and hydrogels using biomaterials. The research activities include rationale design, optimization, and evaluation of the nanoformulations for local, targeted and sustained delivery of biotherapeutic and small molecule drugs using stimuli-responsive polymers, natural polymers, block- and random- copolymers, etc. The ultimate goal of my research laboratory is to develop biomaterials that can provide selective, controlled, non-toxic, biodegradable, and stimuli-responsive platforms to target therapeutic agents to the sites of ocular and inner ear diseases. My laboratory is specialized in the area of (a) sustained delivery of protein/antibodies for the back of eye diseases. (b) non-invasive treatment, and prevention of vision loss due to ocular injuries. (c) next-generation therapeutics for anterior segment ocular diseases (d) nanotherapeutic approaches to provide a prophylactic cure for Chemotherapeutic-Induced Ototoxicity (CIO). 



Grants

New Investigator Grant: "Bio-responsive NanoSensoGel for Prevention of Cisplatin-induced Ototoxity and Hearing Loss"

Presbyterian Health Foundation

07/01/2021 - 06/30/2022

CFAR Grant: "ROS-responsive NanoSensoGel for Prevention of Cistplatin-Induced Ototoxicity and Hearing Loss"

Capita Foundation

11/01/2021 - 12/31/2022

Publications & Presentations

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    21. Starner W D, Li G, Agrahari V, Mitra A K, Kopczynski C. Rapid reversal of corticosteroid-induced ocular hypertension by netarsudil. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017; 58

    22. Agrahari V, Aulgur Z, Thukral S, Dhall N, Conley R, Mitra A K. Recent Patents and Emerging Therapeutics on Ocular Inflammation and Allergy. RECENT PATENTS ON INFLAMMATION & ALLERGY DRUG DISCOVERY. 2017; 11 : 92-106

    23. Mandal A, Cholkar K, Khurana V, Shah A, Agrahari V, Bisht R, Pal D, Mitra A K. Topical Formulation of Self-Assembled Antiviral Prodrug Nanomicelles for Targeted Retinal Delivery. MOLECULAR PHARMACEUTICS. 2017; 14 : 2056-2069

    24. Mandal A, Agrahari V, Khurana V, Pal D, Mitra A K. Transporter effects on cell permeability in drug delivery. EXPERT OPINION ON DRUG DELIVERY. 2017; 14 : 385-401

    25. Agrahari V, Mandal A, Agrahari V, Trinh H M, Joseph M, Ray A, Hadji H, Mitra R, Pal D, Mitra A K. A comprehensive insight on ocular pharmacokinetics. DRUG DELIVERY AND TRANSLATIONAL RESEARCH. 2016; 6 : 735-754

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Grants

    1. Bio-responsive Nano-SensoGel for Prevention of Chemotherapy-Induced Ototoxicity and Hearing Loss . Non-federal. Start Date: 2021. End Date: 2022.




Awards and Honors

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                                                                                            1. American Association Colleges of Pharmacy. American Association Colleges of Pharmacy – New Investigator Award . Date: 2023.  

                                                                                            2. University of Missouri Kansas City, Kansas City, MO. Board of Directors, GAF Women Council. Date: 2022.  

                                                                                            3. Shenandoah University. Bernard J. Dunn, Jr. Faculty Research Award. Date: 2018.  

                                                                                            4. Shenandoah University. Single Discipline Faculty Development Award. Date: 2018.  

                                                                                            5. Society for Laboratory Automation Science. Tony B. Academic Travel Award. Date: 2017.  

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Education
 
                                                          
                        
                                                                                            1.  Degree: Ph D. University of Missouri- Kansas City. Date: 2017.  

                                                                                            2.  Degree: M. Pharm.. Shri G.S. Institute of Technology & Science, India . Date: 2008.  

                                                                                            3.  Degree: B. Pharm. Shri G.S. Institute of Technology & Science, India . Date: 2005.  




                        		 
                                                                                  
                        
                                                                               
 
                   
 
                
     
                
                 	                                        
                    
                                            	                           
                                                
                                                                                                                                                                               
Administrative Assignments
   
                                                         
                        
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