Vibhuti Agrahari, Ph.D.

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Summary

My research focuses on long-term drug delivery by designing innovative systems such as nanocarriers, micelles, and hydrogels using biomaterials. The research activities include rationale design, optimization, and evaluation of the nanoformulations for local, targeted and sustained delivery of biotherapeutic and small molecule drugs using stimuli-responsive polymers, natural polymers, block- and random- copolymers, etc. The ultimate goal of my research laboratory is to develop biomaterials that can provide selective, controlled, non-toxic, biodegradable, and stimuli-responsive platforms to target therapeutic agents to the sites of ocular and inner ear diseases. My laboratory is specialized in the area of (a) sustained delivery of protein/antibodies for the back of eye diseases. (b) non-invasive treatment, and prevention of vision loss due to ocular injuries. (c) next-generation therapeutics for anterior segment ocular diseases (d) nanotherapeutic approaches to provide a prophylactic cure for Chemotherapeutic-Induced Ototoxicity (CIO). 

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Grants

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Publications & Presentations

1. Agrahari V. Dual stimuli-responsive and sustained drug delivery NanoSensoGel formulation for prevention of cisplatin-induced ototoxicity. Journal of Controlled Release. 2024

2. Agrahari V. Analytical considerations to support expeditious formulation development of vaccines. Bioanalysis. 2023

3. Agrahari V, Chauhan H. Polyphenols against infectious diseases: Controlled release nano-formulations. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. 2021; 161 : 66-79

4. Agrahari V, Agrahari V, Chou M, Chew C H, Noll J, Burnouf T. Intelligent micro-/nanorobots as drug and cell carrier devices for biomedical therapeutic advancement: Promising development opportunities and translational challenges. BIOMATERIALS. 2020; 260

5. Agrahari V, Agrahari V, Burnouf P, Chew C H, Burnouf T. Extracellular Microvesicles as New Industrial Therapeutic Frontiers. TRENDS IN BIOTECHNOLOGY. 2019; 37 : 707-729

Grants

1. Bio-responsive Nano-SensoGel for Prevention of Chemotherapy-Induced Ototoxicity and Hearing Loss . Non-federal. Start Date: 2021. End Date: 2022.

Awards and Honors

6. National Biotechnology Conference, AAPS. Biotechnology Graduate Student Symposium Award,. Date: 2016.


7. University of Missouri-Kansas City Preparing Future Faculty Program Scholar Award. Date: 2016.


8. American Association of Pharmaceutical Scientists. Quality by Design and Product Performance Graduate Student Award. Date: 2016.


9. University of Missouri-Kansas City Ronald MacQuarrie Fellowship. Date: 2016.


10. University of Missouri System. Graduate Student Professional Development and Leadership Program. Date: 2015.

Education

1. Degree: Ph D. University of Missouri- Kansas City. Date: 2017.


2. Degree: M. Pharm.. Shri G.S. Institute of Technology & Science, India . Date: 2008.


3. Degree: B. Pharm. Shri G.S. Institute of Technology & Science, India . Date: 2005.

Administrative Assignments

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