Vibhuti Agrahari, Ph.D.

Assistant Professor

Pharmaceutical Sciences

Phone 405-271-6751 x47244

Fax 405-271-7505

Office CPB 325

Email vibhuti-agrahari@ouhsc.edu


Summary

My research focuses on long-term drug delivery by designing innovative systems such as nanocarriers, micelles, and hydrogels using biomaterials. The research activities include rationale design, optimization, and evaluation of the nanoformulations for local, targeted and sustained delivery of biotherapeutic and small molecule drugs using stimuli-responsive polymers, natural polymers, block- and random- copolymers, etc. The ultimate goal of my research laboratory is to develop biomaterials that can provide selective, controlled, non-toxic, biodegradable, and stimuli-responsive platforms to target therapeutic agents to the sites of ocular and inner ear diseases. My laboratory is specialized in the area of (a) sustained delivery of protein/antibodies for the back of eye diseases. (b) non-invasive treatment, and prevention of vision loss due to ocular injuries. (c) next-generation therapeutics for anterior segment ocular diseases (d) nanotherapeutic approaches to provide a prophylactic cure for Chemotherapeutic-Induced Ototoxicity (CIO). 




Grants

New Investigator Grant: "Bio-responsive NanoSensoGel for Prevention of Cisplatin-induced Ototoxity and Hearing Loss"

Presbyterian Health Foundation

07/01/2021 - 06/30/2022

CFAR Grant: "ROS-responsive NanoSensoGel for Prevention of Cistplatin-Induced Ototoxicity and Hearing Loss"

Capita Foundation

11/01/2021 - 12/31/2022


Publications & Presentations

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    1. Thakur N S, Rus I, Agrahari V. A multimodal approach to smart and sustained drug delivery for corneal wound management: the GelPol nanoformulation. Nanomedicine (Lond) . 2025 Sep;20(18):2321-2339. 2025

    2. Chakrabarty B, Thakur N S, Joshi A D, Agrahari V. Rationally designed sodium thiosulfate-loaded solid lipid nanoparticles for inner ear delivery and prevention of medication-induced ototoxicity. J Mater Chem B . 2025 Nov 19;13(45):14690-14703. 2025

    3. Agrahari V, Boddu S. Advancing Vision: The Role of Printing Technologies in Therapeutic Ocular Contact Lens Innovation. American Association of Pharmaceutical Scientists (AAPS) . 2025

    4. Robbins B T, Montreuil K A, Kundu N, Kumar P, Agrahari V. Corneal Treatment, Repair, and Regeneration: Exosomes at Rescue. Pharmaceutics. 2024; 16 : 1424

    5. Montreuil K A, Thakur N, Robbins B T, Chakrabarty B, Agrahari V. Design and Development of Long-Term Therapy for Corneal Repair and Healing – ‘Nanoparticles-in-Dual-Gels’. American Journal of Pharmaceutical Education. 2024; 88 : 100918

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Grants

    1. Bio-responsive Nano-SensoGel for Prevention of Chemotherapy-Induced Ototoxicity and Hearing Loss . Non-federal. Start Date: 2021. End Date: 2022.




Awards and Honors

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                                                                                            1. American Association Colleges of Pharmacy. American Association Colleges of Pharmacy – New Investigator Award . Date: 2023.  

                                                                                            2. University of Missouri Kansas City, Kansas City, MO. Board of Directors, GAF Women Council. Date: 2022.  

                                                                                            3. Shenandoah University. Bernard J. Dunn, Jr. Faculty Research Award. Date: 2018.  

                                                                                            4. Shenandoah University. Single Discipline Faculty Development Award. Date: 2018.  

                                                                                            5. Society for Laboratory Automation Science. Tony B. Academic Travel Award. Date: 2017.  

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Education

                                                                                            1.  Degree: Ph D. University of Missouri- Kansas City. Date: 2017.  

                                                                                            2.  Degree: M. Pharm.. Shri G.S. Institute of Technology & Science, India . Date: 2008.  

                                                                                            3.  Degree: B. Pharm. Shri G.S. Institute of Technology & Science, India . Date: 2005.  




Administrative Assignments


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