1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.
Vibhudutta Awasthi, Ph.D.
Professor and Associate Dean for Research
Pharmaceutical Sciences
Phone (405) 271-6593 x47331
Fax (405) -271-7505
Office CPB 309
Summary
My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.
Publications & Presentations
- 36. Awasthi S, Singh B, Ramani V, Awasthi V, Xie J, Kosanke S. A TLR4-interacting surfactant protein-A-derived peptide improves host defense against Pseudomonas aeruginosa. JOURNAL OF IMMUNOLOGY. 2016; 196
37. Pathuri G, Hedrick A F, Awasthi V, Cowley, Jr B D, Gali H. Synthesis and in vivo evaluation of ortho-[124I]iodohippurate for PET renography in healthy rats. Appl Radiat Isot. 2016; 115 : 251-5
38. Yadav V R, Rao G, Houson H, Hedrick A, Awasthi S, Roberts P R, Awasthi V. Nanovesicular liposome-encapsulated hemoglobin (LEH) prevents multi-organ injuries in a rat model of hemorrhagic shock. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016; 93 : 97-106
39. Rao G, Yadav V, Awasthi S, Roberts P, Awasthi V. Effect of liposome-encapsulated hemoglobin resuscitation on proteostasis in small intestinal epithelium after hemorrhagic shock. Am J Physiol Gastrointest Liver. 2016; 311 : G180-189
40. Nkepang G N, Hedrick A F, Awasthi V, Gali H. Facile synthesis of para-[18F]fluorohippurate via iodonium ylide-mediated radiofluorination for PET renography. Bioorg Med Chem Lett. 2016; 26 : 479-83
Grants
- 1. Developing PPARĪ³ acetylation inhibitor for the treatment of aging-related conditions. NIH. Start Date: 2021. End Date: 2026.
2. Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment. NIH. Start Date: 2021. End Date: 2026.
3. SBIR Phase I: Early-Stage Development of GPPD for Fatty Liver. NIH.
4. Surfactant protein-A regions as TLR4-immunomodulators. NIH. Start Date: 2017. End Date: 2023.
5. STTR Phase I: Cardiotropic Atorvastatin Liposomes for Myocardial Reperfusion Injury. NSF. Start Date: 2023. End Date: 2021.
Awards and Honors
- 1. USPTO. Patent application issued. Date: 2015.
2. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.
3. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.
4. Sandra K and David L Gilliland Chair in Nuclear Pharmacy . Date: 2012.
Education
- 1. Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.
2. Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.
3. Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.
Administrative Assignments
2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.
External Connections and Partnerships
no results