Vibhudutta Awasthi, Ph.D.

Professor and Associate Dean for Research

Pharmaceutical Sciences

Phone (405) 271-6593 x47331

Fax (405) -271-7505

Office CPB 309

Email vibhudutta-awasthi@ouhsc.edu


Summary


My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.



Publications & Presentations

    76. Awasthi S, Awasthi V. Distribution of dendritic cells after intranasal immunization in mice. Clinical Nuclear Medicine. 2005; 30 : 205

    77. Awasthi S, Awasthi V, Magee D M, Coalson J J. Efficacy of antigen 2/proline-rich antigen cDNA-transfected dendritic cells in immunization of mice against Coccidioides posadasii. Journal of immunology (Baltimore, Md. : 1950). 2005; 175 : 3900-6

    78. Awasthi S, Awasthi V. Regulation of pulmonary surfactant by growth factors and cytokines during lung injury . Research Signpost. 2002; 2 : 223-238

    79. Awasthi S, Vivekananda J, Awasthi V, Smith D, King R J. CTP:phosphocholine cytidylyltransferase inhibition by ceramide via PKC-alpha, p38 MAPK, cPLA2, and 5-lipoxygenase. American journal of physiology. Lung cellular and molecular physiology. 2001; 281 : L108-18

    80. Vivekananda J, Awasthi V, Awasthi S, Smith D B, King R J. Hepatocyte growth factor is elevated in chronic lung injury and inhibits surfactant metabolism. American journal of physiology. Lung cellular and molecular physiology. 2000; 278 : L382-92




Grants

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    6. Pharmacotherapy of Traumatic Brain Injury Accompanied by Hemorrhagic Shock. NIH. Start Date: 2017. End Date: 2022.

    7. Development of Bioactive Peptides for the Inhibition of Neuroinflammation and Neurotoxicity Induced by Amyloid-beta. Non-federal. Start Date: 2020. End Date: 2021.

    8. Immunokinetics of superhydrophilic polymer-modified liposome encapsulated hemoglobin. Non-federal. Start Date: 2017. End Date: 2020.

    9. PET Imaging Agent For Myocardial Infarction. NIH. Start Date: 2019. End Date: 2019.

    10. Development of Tumor Proliferation PET Tracer FLT using a Low Cost Single Dose Automatic Production and Quality Control Biomarker Generator System. NIH. Start Date: 2016. End Date: 2017.

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Awards and Honors

                                                                                            1. USPTO. Patent application issued. Date: 2015.  

                                                                                            2. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.  

                                                                                            3. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.  

                                                                                            4. Sandra K and David L Gilliland Chair in Nuclear Pharmacy . Date: 2012.  




Education

                                                                                            1.  Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.  

                                                                                            2.  Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.  

                                                                                            3.  Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.  




Administrative Assignments

                                                

    1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.

                                                

    2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.




External Connections and Partnerships


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