Vibhudutta Awasthi, Ph.D.

Professor and Associate Dean for Research

Pharmaceutical Sciences

Phone (405) 271-6593 x47331

Fax (405) -271-7505

Office CPB 309

Email vibhudutta-awasthi@ouhsc.edu


Summary


My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.



Publications & Presentations

    46. Rao G, Croft B, Teng C, Awasthi V. Ubiquitin-proteasome system in neurodegenerative disorders. J Drug Metab Toxicol . 2015; 6 : 187

    47. Rao G, Xie J, Hedrick A, Awasthi V. Hemorrhagic shock-induced cerebral bioenergetic imbalance is corrected by pharmacologic treatment with EF24 in a rat model. Neuropharmacology. 2015; 99 : 318-327

    48. Jackson K, Christiansen V J, Yadav V R, Silasi-Mansat R, Lupu F, Awasthi V, Zhang R R, McKee P A. Suppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase. Neoplasia. 2015; 17 : 23-54

    49. Awwad H O, Gonzalez L P, Tompkins P, Lerner M, Brackett D J, Awasthi V, Standifer K. Blast Overpressure Waves Induce Transient Anxiety and Regional Changes in Cerebral Glucose Metabolism and Delayed Hyperarousal in Rats. Frontiers in neurology. 2015; 6 : 132

    50. Rao G, Hedrick A, Yadav V, Xie J, Awasthi V, Hussain A. The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin (LEH) in a rat model of hypovolemic shock. J Cereb Blood Flow Metab. 2015; 35 : 1528-1536




Grants

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    6. STTR Phase I: Cardiotropic Atorvastatin Liposomes for Myocardial Reperfusion Injury. NSF. Start Date: 2023. End Date: 2021.

    7. Pharmacotherapy of Traumatic Brain Injury Accompanied by Hemorrhagic Shock. NIH. Start Date: 2017. End Date: 2022.

    8. Development of Bioactive Peptides for the Inhibition of Neuroinflammation and Neurotoxicity Induced by Amyloid-beta. Non-federal. Start Date: 2020. End Date: 2021.

    9. Immunokinetics of superhydrophilic polymer-modified liposome encapsulated hemoglobin. Non-federal. Start Date: 2017. End Date: 2020.

    10. PET Imaging Agent For Myocardial Infarction. NIH. Start Date: 2019. End Date: 2019.

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Awards and Honors

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                                                                                            1. USPTO. Patent application issued. Date: 2015.  

                                                                                            2. Indo-American Society of Nuclear Medicine (IASNM)Outstanding Presidential Award . Date: 2015.  

                                                                                            3. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.  

                                                                                            4. OUHSC-College of Pharmacy. USP Convention Voting Delegate. Date: 2014.  

                                                                                            5. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.  

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Education

                                                                                            1.  Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.  

                                                                                            2.  Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.  

                                                                                            3.  Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.  




Administrative Assignments

                                                

    1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.

                                                

    2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.




External Connections and Partnerships


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