Shanjana Awasthi, Ph.D.

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Summary

Research in my lab is focused on developing immunotherapeutics and vaccines by harnessing our body's natural host defense mechanisms. Our research efforts have been focused on developing TLR4-interacting surfactant protein-A-derived peptides and dendritic cell-based vaccine approaches. We are interested in investigating the mechanisms of action and efficacy of these approaches using structural, computational, physicochemical, and immunological tools and methods, and in vitro and in animal models of infection, inflammation and cancer.

Certifications & Licenses

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Publications & Presentations

16. Awasthi S, Kumar G, Xie J, Beierle J, Awasthi V, Ramani V, Singh B, Breshears M, Kosanke S. Toll-like receptor-4-interacting surfactant protein-A-derived peptide reduces inflammation in a mouse model of intratracheal lipopolysaccharide challenge. The Journal of Immunology. 2018; 200 : 174.10-174.10

17. Awasthi S. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells. Springer New York. 2017

18. Yadav V R, Rao G, Houson H, Hedrick A, Awasthi S, Roberts P R, Awasthi V. Nanovesicular liposome-encapsulated hemoglobin (LEH) prevents multi-organ injuries in a rat model of hemorrhagic shock. European Journal of Pharmaceutical Sciences. 2016; 93 : 97-106

19. Rao G, Yadav V, Awasthi S, Roberts P, Awasthi V. Effect of liposome-encapsulated hemoglobin resuscitation on proteostasis in small intestinal epithelium after hemorrhagic shock. Am J Physiol Gastrointest Liver. 2016; 311 : G180-189

20. Awasthi S, Singh B, Ramani V, Awasthi V, Xie J, Kosanke S. A TLR4-interacting surfactant protein-A-derived peptide improves host defense against Pseudomonas aeruginosa. The Journal of Immunology. 2016; 196 : 65.24-65.24

Grants

11. une functions of dendritic cells, TLR and collectins in preterm baboon lung. Non-federal. Start Date: 2007. End Date: 2008.

12. Role of dendritic cells & pathogen-pattern recognition receptors in preterm baboon lung. Non-federal. Start Date: 2004. End Date: 2007.

13. Development of dendritic cell-based vaccine against Coccidioides immitis.. Non-federal. Start Date: 2003. End Date: 2004.

14. Health effects of environmental exposure to Stachybotrys chartarum in mice. Non-federal. Start Date: 2002. End Date: 2003.

Awards and Honors

21. Sanjay Gandhi Institute of Medical Sciences. Research fellowship . Date: 1991.


22. National Scholarship Program, India. National Scholarship. Date: 1991.


23. MKP College/HNM Garhwal University. Gold Medal and certificates for academic achievements. Date: 1991.


24. High-School. Received certificate and award for academic achievement. Date: 1991.


25. Uttar Pradesh State. Received scholarship for academic achievements. Date: 1991.

Education

1. Degree: Post-Baccalaureate Categorical certificate in Clinical Microbiology. University of Texas Health Sciences Center at San Antonio. Date: 2006.


2. Degree: Ph D. Sanjay Gandhi Post Graduate Institute of Medical Sciences. Date: 1995.


3. Degree: MS. Indian Institute of Technology (IIT). Date: 1990.


4. Degree: BS. MKP College, HNM Garhwal University. Date: 1988.

Administrative Assignments

no results

External Connections and Partnerships

1. Type: Funding. Org: Oklahoma State University (year 2013- year 2017). City: Stillwater. State: Oklahoma. NIH-supported COBRE program in Respiratory and Infectious Diseases. Date: 2013.


2. Type: Funding. Org: University of Oklahoma (year 2013- year 2014). City: Norman. State: Oklahoma. NIH-supported COBRE program in Structural Biology. Date: 2013.