Shanjana Awasthi, Ph.D.

Associate Professor

Department of Pharmaceutical Sciences

Phone (405) 271-6593 x47332

Fax (405) 271-7505

Office CPB 324

Email shanjana-awasthi@ouhsc.edu


Summary

Research in my lab is focused on developing immunotherapeutics and vaccines by harnessing our body's natural host defense mechanisms. Our research efforts have been focused on developing TLR4-interacting surfactant protein-A-derived peptides and dendritic cell-based vaccine approaches. We are interested in investigating the mechanisms of action and efficacy of these approaches using structural, computational, physicochemical, and immunological tools and methods, and in vitro and in animal models of infection, inflammation and cancer.


List of current grants



Education & Experience

Ph.D. in Microbiology

Sanjay Gandhi P.G. Institute of Medical Sciences, Lucknow, India

1995

M.Sc. in Biosciences

Indian Institute of Technology, Roorkee, India

1990

B.Sc. in Zoology, Botany, Chemistry

MKP College/HNB University, Dehradun, India

1988

Certifications & Licenses

Categorical certificate in Clinical Microbiology

UTHSCSA, TX

2006

Certified in Clinical Microbiology

American Society of Clinical Pathologists



Publications & Presentations

1 2 3 4 > >>
  1. Awasthi S, Rahman N, Hedrick A, Awasthi V, Breshears M, Kosanke S. Analysis of health and lung injury markers in mice treated with TLR4-interacting SPA4 peptide. Journal of Immunology (Annual Meeting Abstracts). 2019; 202 : 64.26
  2. Awasthi S, Vilekar P, Conkleton A, Rahman N. Dendritic cell-based immunization induces Coccidioides Ag2/PRA-specific immune response. Vaccine. 2019; 37 : 1685-1691
  3. Awasthi S, Singh B, Ramani V, Xie J, Kosanke S. TLR4-interacting SPA4 peptide improves host defense and alleviates tissue injury in a mouse model of Pseudomonas aeruginosa lung infection. PloS one. 2019; 14 : e0210979
  4. Awasthi S, Kumar G, Xie J, Beierle J, Awasthi V, Ramani V, Singh B, Breshears M, Kosanke S. Toll-like receptor-4-interacting surfactant protein-A-derived peptide reduces inflammation in a mouse model of intratracheal lipopolysaccharide challenge. Journal of Immunology (Annual Meeting Abstracts). 2018; 200 : 174.10
  5. Awasthi S. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells. Methods Mol Biol. 2017; 1625 : 75-83
1 2 3 4 > >>