Shanjana Awasthi, Ph.D.

Associate Professor

Department of Pharmaceutical Sciences

Phone (405) 271-6593 x47332

Fax (405) 271-7505

Office CPB 324

Email shanjana-awasthi@ouhsc.edu


Summary

Research in my lab is focused on developing immunotherapeutics and vaccines by harnessing our body's natural host defense mechanisms. Our research efforts have been focused on developing TLR4-interacting surfactant protein-A-derived peptides and dendritic cell-based vaccine approaches. We are interested in investigating the mechanisms of action and efficacy of these approaches using structural, computational, physicochemical, and immunological tools and methods, and in vitro and in animal models of infection, inflammation and cancer.



Education & Experience

Ph.D. in Microbiology

Sanjay Gandhi P.G. Institute of Medical Sciences, Lucknow, India

1995

M.Sc. in Biosciences

Indian Institute of Technology, Roorkee, India

1990

B.Sc. in Zoology, Botany, Chemistry

MKP College/HNB University, Dehradun, India

1988

Certifications & Licenses

Categorical certificate in Clinical Microbiology

UTHSCSA, TX

2006

Certified in Clinical Microbiology

American Society of Clinical Pathologists



Honors & Awards

Professional Awards

Travel Award

American Association of Immunologists

Teaching Excellence Course

UTHSCA, San Antonio, TX

Postdoctoral Travel Award (for presentation at meeting)

Society of Leukocyte Biology




Publications & Presentations

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  • Awasthi S. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells. Methods Mol Biol. 2017; 1625 : 75-83
  • Yadav V R, Rao G, Houson H, Hedrick A, Awasthi S, Roberts P R, Awasthi V. Nanovesicular liposome-encapsulated hemoglobin (LEH) prevents multi-organ injuries in a rat model of hemorrhagic shock. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016; 93 : 97-106
  • Rao G, Yadav V, Awasthi S, Roberts P, Awasthi V. Effect of liposome-encapsulated hemoglobin resuscitation on proteostasis in small intestinal epithelium after hemorrhagic shock. Am J Physiol Gastrointest Liver. 2016; 311 : G180-189
  • Ramani V, Awasthi S. Toll-like receptor 4-interacting SPA4 peptide suppresses the NLRP3 inflammasome in response to LPS and ATP stimuli. J Leukocyte Biol. 2015; 98 : 1037-48
  • Vilekar P, Rao G, Awasthi S, Awasthi V,. Diphenyldifluoroketone EF24 suppresses pro-inflammatory interleukin-1 receptor 1 and toll-like receptor 4 in lipopolysaccharide-stimulated dendritic cells. J Inflamm. 2015; 12 : 55
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