Shanjana Awasthi, Ph.D.

Associate Professor

Department of Pharmaceutical Sciences

Phone (405) 271-6593 x47332

Fax (405) 271-7505

Office CPB 324



Research in my lab is focused on developing immunotherapeutics and vaccines by harnessing our body's natural host defense mechanisms. Our research efforts have been focused on developing TLR4-interacting surfactant protein-A-derived peptides and dendritic cell-based vaccine approaches. We are interested in investigating the mechanisms of action and efficacy of these approaches using structural, computational, physicochemical, and immunological tools and methods, and in vitro and in animal models of infection, inflammation and cancer.

Education & Experience

Ph.D. in Microbiology

Sanjay Gandhi P.G. Institute of Medical Sciences, Lucknow, India


M.Sc. in Biosciences

Indian Institute of Technology, Roorkee, India


B.Sc. in Zoology, Botany, Chemistry

MKP College/HNB University, Dehradun, India


Certifications & Licenses

Categorical certificate in Clinical Microbiology



Certified in Clinical Microbiology

American Society of Clinical Pathologists

Honors & Awards

Professional Awards

Travel Award

American Association of Immunologists

Teaching Excellence Course

UTHSCA, San Antonio, TX

Postdoctoral Travel Award (for presentation at meeting)

Society of Leukocyte Biology

Publications & Presentations

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  1. Awasthi S, Singh B, Ramani V, Xie J, Kosanke S. TLR4-interacting SPA4 peptide improves host defense and alleviates tissue injury in a mouse model of Pseudomonas aeruginosa lung infection. PloS one. 2019; 14 : e0210979
  2. Awasthi S, Kumar G, Xie J, Beierle J, Awasthi V, Ramani V, Singh B, Breshears M, Kosanke S. Toll-like receptor-4-interacting surfactant protein-A-derived peptide reduces inflammation in a mouse model of intratracheal lipopolysaccharide challenge. Journal of Immunology. 2018; 174.10
  3. Awasthi S. Intranasal Antifungal Vaccination Using DNA-Transfected Dendritic Cells. Methods Mol Biol. 2017; 1625 : 75-83
  4. Yadav V R, Rao G, Houson H, Hedrick A, Awasthi S, Roberts P R, Awasthi V. Nanovesicular liposome-encapsulated hemoglobin (LEH) prevents multi-organ injuries in a rat model of hemorrhagic shock. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016; 93 : 97-106
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  • Surfactant protein-A regions as TLR4-immunomodulators. 2017.
  • TLR4-interacting SPA4 peptide: A novel therapeutic. 2000.
  • Control of lung inflammation by a TLR4-interacting SP-A-derived peptide. 2013.
  • TLR4-immunomodulation by a surfactant protein-A peptide. 2000.
  • Evaluation of a TLR4-interacting peptide in colon cancer. 2000.
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