H. Anne Pereira, Ph.D.

Dean, Graduate College and David L. Boren Professor

Pharmaceutical Sciences

Phone (405) 271-6593 x58034

Fax (405) 271-7505

Office CPB 329

Email anne-pereira@ouhsc.edu


Summary

My laboratory investigates the role of a novel inflammatory mediator known as CAP37. We focus on the significance of this protein in host defense against severe infections including infections of the eye and in various inflammatory mediated diseases such as atherosclerosis and Alzheimer's disease. We currently employ a combination of cellular, immunological, biochemical and molecular approaches at the in vitro and in vivo level to solve these questions. Our long-term goals are to design new and effective antibiotics and anti-inflammatory therapeutics.



Research

This laboratory investigates the role of a novel inflammatory mediator known as CAP37. We focus on the significance of this protein in host defense against severe infections including infections of the eye and in various inflammatory mediated diseases such as atherosclerosis and Alzheimer's disease. We currently employ a combination of cellular, immunological, biochemical and molecular approaches at the in vitro and in vivo level to solve these questions. Our long-term goals are to design new and effective antibiotics and anti-inflammatory therapeutics.



Patents

Biomarker and method for detecting a chronic inflammatory-associated disease

Patent No. 8,450,071

USA

H. Anne Pereira



Publications & Presentations

<< 2 3 4 5 6 7 8 > >>
    21. Pereira H A. Novel therapies based on cationic antimicrobial peptides. Current pharmaceutical biotechnology. 2006; 7 : 229-34

    22. Pereira H A, Ruan X, Gonzalez M L, Tsyshevskaya-Hoover I, Chodosh J. Modulation of corneal epithelial cell functions by the neutrophil-derived inflammatory mediator CAP37. Investigative ophthalmology & visual science. 2004; 45 : 4284-92

    23. Gonzalez M L, Ruan X, Kumar P, Grammas P, Pereira H A. Functional modulation of smooth muscle cells by the inflammatory mediator CAP37. Microvascular research. 2004; 67 : 168-81

    24. Lee T D, Gonzalez M L, Kumar P, Grammas P, Pereira A. CAP37, a neutrophil-derived inflammatory mediator, augments leukocyte adhesion to endothelial monolayers. Microvascular research. 2003; 66 : 38-48

    25. Pereira H A, Ruan X, Kumar P. Activation of microglia: a neuroinflammatory role for CAP37. Glia. 2003; 41 : 64-72

<< 2 3 4 5 6 7 8 > >>



Grants

<< 2 3 4 5
    21. Role of CAP37 in Neuroinflammation: Friend or Foe?. State Agency. Start Date: 2012. End Date: 2015.

    22. Development of an antimicrobial peptide therapeutic for Pseudomonas aeruginosa. NIH. Start Date: 2007. End Date: 2014.

<< 2 3 4 5



Awards and Honors

<< 1 2 3 4 >>
                                                                                            11. American Heart Association. Established Investigator. Date: 1998.  

                                                                                            12. OUHSC. Provosts' Research Award to Junior Faculty. Date: 1994.  

                                                                                            13. American Lung Association. American Lung Association Research Award. Date: 1990.  

                                                                                            14. Gordon Research Conference on Phagocytes, New Hampshire. Travel Scholarship. Date: 1987.  

                                                                                            15. University of Melbourne, Australia. BSc (Honours) First Class Honours and First Place. Date: 1977.  

<< 1 2 3 4 >>



Education

                                                                                            1.  Degree: Ph D. University of Melbourne. Date: 1982.  

                                                                                            2.  Degree: BSc (Honours) First class honours & First Place. University of Melbourne. Date: 1976.  

                                                                                            3.  Degree: BS. University of Melbourne. Date: 1975.  




Administrative Assignments

                                                

    1. Role: Dean. Scope: University. Description: Dean of the Graduate College. Responsible for Graduate Programs on the Health Sciences Campus and the Postdoctoral Office. Date: 2014.

                                                

    2. Role: Associate Dean. Scope: College. Description: Responsible for Oversight of research activities in the College of Pharmacy, mentoring junior faculty and trainees. Date: 2009.