H. Anne Pereira, Ph.D.

Dean, Graduate College and David L. Boren Professor

Pharmaceutical Sciences

Phone (405) 271-6593 x58034

Fax (405) 271-7505

Office CPB 329

Email anne-pereira@ouhsc.edu


Summary

My laboratory investigates the role of a novel inflammatory mediator known as CAP37. We focus on the significance of this protein in host defense against severe infections including infections of the eye and in various inflammatory mediated diseases such as atherosclerosis and Alzheimer's disease. We currently employ a combination of cellular, immunological, biochemical and molecular approaches at the in vitro and in vivo level to solve these questions. Our long-term goals are to design new and effective antibiotics and anti-inflammatory therapeutics.



Research

This laboratory investigates the role of a novel inflammatory mediator known as CAP37. We focus on the significance of this protein in host defense against severe infections including infections of the eye and in various inflammatory mediated diseases such as atherosclerosis and Alzheimer's disease. We currently employ a combination of cellular, immunological, biochemical and molecular approaches at the in vitro and in vivo level to solve these questions. Our long-term goals are to design new and effective antibiotics and anti-inflammatory therapeutics.



Patents

Biomarker and method for detecting a chronic inflammatory-associated disease

Patent No. 8,450,071

USA

H. Anne Pereira



Publications & Presentations

<< 1 2 3 4 5 > >>
    6. Griffith G L, Kasus-Jacobi A, Pereira A. Bioactive Antimicrobial Peptides as Therapeutics for Corneal Wounds and Infections. Advances in wound care. 2017; 6 : 175-190

    7. Kasus-Jacobi A, Griffith G L, Lerner M, Pereira A. Effect of Cationic Antimicrobial Protein CAP37 on Cytokine Profile during Corneal Wound Healing. Journal of ocular diseases and therapeutics. 2017; 5 : 19-27

    8. Makoni M, Eckert J, Pereira H A, Nizet V, Lawrence S M. Alterations in neonatal function attributable to increased immature forms. Early Human Development. 2016

    9. Casanegra A, Stoner J A, Tafur A J, Pereira H A, Rathbun S W, Gardner A W. Differences in galectin-3, a biomarker of fibrosis, between participants with peripheral arterial disease and participants with normal ankle-brachial index. Vascular Medicine. 2016

    10. Stock A J, Kasus-Jacobi A, Wren J, Sjoelund V, Prestwich G, Pereira H A. The role of neutrophil proteins on the amyloid beta-RAGE axis. Plos One. 2016

<< 1 2 3 4 5 > >>



Grants

<< 1 2 3 4 5 >>
    6. Molecular Basis of Immunity. NIH. Start Date: 2018. End Date: 2023.

    7. OU Entrepreneurship Roadmap. Misc Federal. Start Date: 2021. End Date: 2022.

    8. OSCTR Community Engaged Research Exploratory Award. NIH. Start Date: 2021. End Date: 2022.

    9. Development of Bioactive Peptides for the Inhibition of Neuroinflammation and Neurotoxicity Induced by Amyloid-beta. Non-federal. Start Date: 2020. End Date: 2021.

    10. Novel Peptide Therapeutic for Corneal Wound Healing and Infections. Misc Non-Federal. Start Date: 2019. End Date: 2020.

<< 1 2 3 4 5 >>



Awards and Honors

<< 1 2 3 4 >>
                                                                                            11. American Heart Association. Established Investigator. Date: 1998.  

                                                                                            12. OUHSC. Provosts' Research Award to Junior Faculty. Date: 1994.  

                                                                                            13. American Lung Association. American Lung Association Research Award. Date: 1990.  

                                                                                            14. Gordon Research Conference on Phagocytes, New Hampshire. Travel Scholarship. Date: 1987.  

                                                                                            15. University of Melbourne, Australia. BSc (Honours) First Class Honours and First Place. Date: 1977.  

<< 1 2 3 4 >>



Education

                                                                                            1.  Degree: Ph D. University of Melbourne. Date: 1982.  

                                                                                            2.  Degree: BSc (Honours) First class honours & First Place. University of Melbourne. Date: 1976.  

                                                                                            3.  Degree: BS. University of Melbourne. Date: 1975.  




Administrative Assignments

                                                

    1. Role: Dean. Scope: University. Description: Dean of the Graduate College. Responsible for Graduate Programs on the Health Sciences Campus and the Postdoctoral Office. Date: 2014.

                                                

    2. Role: Associate Dean. Scope: College. Description: Responsible for Oversight of research activities in the College of Pharmacy, mentoring junior faculty and trainees. Date: 2009.