1. Role: Dean. Scope: University. Description: Dean of the Graduate College. Responsible for Graduate Programs on the Health Sciences Campus and the Postdoctoral Office. Date: 2014.
H. Anne Pereira, Ph.D.
Dean, Graduate College and David L. Boren Professor
Pharmaceutical Sciences
Phone (405) 271-6593 x58034
Fax (405) 271-7505
Office CPB 329
Email anne-pereira@ouhsc.edu
Summary
My laboratory investigates the role of a novel inflammatory mediator known as CAP37. We focus on the significance of this protein in host defense against severe infections including infections of the eye and in various inflammatory mediated diseases such as atherosclerosis and Alzheimer's disease. We currently employ a combination of cellular, immunological, biochemical and molecular approaches at the in vitro and in vivo level to solve these questions. Our long-term goals are to design new and effective antibiotics and anti-inflammatory therapeutics.
Research
This laboratory investigates the role of a novel inflammatory mediator known as CAP37. We focus on the significance of this protein in host defense against severe infections including infections of the eye and in various inflammatory mediated diseases such as atherosclerosis and Alzheimer's disease. We currently employ a combination of cellular, immunological, biochemical and molecular approaches at the in vitro and in vivo level to solve these questions. Our long-term goals are to design new and effective antibiotics and anti-inflammatory therapeutics.
Patents
Biomarker and method for detecting a chronic inflammatory-associated disease
Patent No. 8,450,071
USA
H. Anne Pereira
Publications & Presentations
- 21. Pereira H A. Novel therapies based on cationic antimicrobial peptides. Current pharmaceutical biotechnology. 2006; 7 : 229-34
22. Pereira H A, Ruan X, Gonzalez M L, Tsyshevskaya-Hoover I, Chodosh J. Modulation of corneal epithelial cell functions by the neutrophil-derived inflammatory mediator CAP37. Investigative ophthalmology & visual science. 2004; 45 : 4284-92
23. Gonzalez M L, Ruan X, Kumar P, Grammas P, Pereira H A. Functional modulation of smooth muscle cells by the inflammatory mediator CAP37. Microvascular research. 2004; 67 : 168-81
24. Lee T D, Gonzalez M L, Kumar P, Grammas P, Pereira A. CAP37, a neutrophil-derived inflammatory mediator, augments leukocyte adhesion to endothelial monolayers. Microvascular research. 2003; 66 : 38-48
25. Pereira H A, Ruan X, Kumar P. Activation of microglia: a neuroinflammatory role for CAP37. Glia. 2003; 41 : 64-72
Grants
- 16. 49th Annual Meeting of the Society for Leukocyte Biology - Inflammation, Immunity and Cancer: Neutrophils and Other leukocytes. NIH. Start Date: 2016. End Date: 2017.
17. Molecular Basis of Immunity. NIH. Start Date: 2012. End Date: 2017.
18. Novel topical peptide therapeutic for the treatment of wounds infected with antibiotic resistant Gram negative bacteria. Non-federal. Start Date: 2016. End Date: 2017.
19. Wound healing mechanisms modulated by novel antimicrobial peptide. Misc Non-Federal. Start Date: 2015. End Date: 2016.
20. 48th Annual Meeting of the Society for leukocyte Biology - Immunity in Health and Disease. NIH. Start Date: 2015. End Date: 2016.
Awards and Honors
- 1. University of Oklahoma Health Sciences Center. David L Boren Professorship. Date: 2018.
2. College of Pharmacy. Herbert and Dorothy Langsam Chair. Date: 2018.
3. Oklahoma BioScience Association. OK Bio Researcher Recognition Award -Winner. Date: 2016.
4. Journal Record. Journal Record Innovator of the Year. Date: 2016.
5. National Academy of Inventors. Fellow. Date: 2015.
Education
- 1. Degree: Ph D. University of Melbourne. Date: 1982.
2. Degree: BSc (Honours) First class honours & First Place. University of Melbourne. Date: 1976.
3. Degree: BS. University of Melbourne. Date: 1975.
Administrative Assignments
2. Role: Associate Dean. Scope: College. Description: Responsible for Oversight of research activities in the College of Pharmacy, mentoring junior faculty and trainees. Date: 2009.