Clinical and Translational Science Fellowship in Pediatric Pharmacotherapy

This three-year program is designed to provide skills that are necessary to pursue a career in academia, clinical research and basic clinical practice focused in pediatric pharmacotherapy. The program integrates a formal hands-on laboratory experience in pharmacokinetics and pharmacodynamics (75%), teaching both in the classroom and experiential (10%), and practical clinical experience in pediatrics (15%). A major focus of this program is in clinical pharmacokinetics and pharmacodynamics to optimize the efficacy and safety of medications in pediatric and neonatal critically-ill children.  Upon completion of this program, the fellow will possess a broad base in pediatric clinical pharmacy, enhanced professional maturity and will exhibit confidence in their research and teaching abilities in a variety of educational settings.



Fellowship Objectives

  • Prepare a research protocol and submit to the OUHSC Institutional Review Board.
    1. Develop scientific hypothesis.
    2. Develop experimental methods to test the hypothesis.
  • Demonstrate ability to identify funding opportunities for projects and apply for 1-2 grants funding for extramural funding consideration. 
  • Publish (peer-reviewed) and present results of a research project at a national meeting.
  • Complete Masters of Science in Clinical and Translational Science.
  • Complete requirements for the Advanced Teaching Skills for Residents/Fellows teaching certificate.


Practice and Research Site

The Downtown Campus of the OU Medical System in Oklahoma City is comprised of two hospitals: OU Medical Center and The Children's Hospital at OU Medical Center. The Children's Hospital at OU Medical Center is a 314-bed teaching hospital with an 93-bed Neonatal ICU and 25-bed Pediatric ICU. It is the only comprehensive children's hospital in the state of Oklahoma. 



Required Rotations

The fellow will spend no more than 15% of time in clinical experience practice activities.  Clinical training activities will focus in pediatric nephrology and pediatric and neonatal critical care to provide exposure of the fellow to the background of the research projects and to promote fostering of clinical skills.  The fellow will complete six, one-month rotations as specified below.

Year of Program/Clinical Rotations

  • Year 1
    • Medical Pediatrics ICU
    • Neonatal ICU I
  • Year 2
    • Cardiovascular Pediatric ICU
    • Pediatric Nephrology
  • Year 3
    • Neonatal ICU II
    • General Pediatrics (Precepting rotation)


Teaching

The fellow will have several opportunities for didactic and experiential teaching at the OU College of Pharmacy and The Children’s Hospital at OU Medical Center. 

  • 1-2 lectures in the Doctor of Pharmacy program per year.
  • Participation in selected small group facilitation, lab work, and course coordination activities.
  • Participation in interdisciplinary in-services and miscellaneous education activities at The Children’s Hospital at OU Medical Center.
  • Assume primary precepting responsibility for P4 students during the latter part of the fellowship.


Research Training

As part of this program, the fellow will be expected to complete the Masters of Science of Clinical and Translational Science with the OU Gradate College at the OUHSC  (http://graduate.ouhsc.edu/Portals/1056/Assets/documents/CTS/MSinCTSProgram021710_000.pdf). 

As part of this program, the fellow will be required to write a thesis on one of their assigned translational science research projections under the supervision of Dr. Johnson and an assigned thesis committee.

An example plan of study is described below.

Year of Program 1

  • Fall Semester (Course/Credit)
    • Foundations of Clinical Research/3
    • Principles of Epidemiology/3
  • Spring Semester (Course/Credit)
    • Foundations of Translational Research/3
    • Biostat Methods I/3
  • Summer Semester (Course/Credit)
    • Grants Management/2

Year of Program 2

  • Fall Semester (Course/Credit)
    • App of Computers in Analysis/3
    • Cultural Practicum/1
  • Spring Semester (Course/Credit)
    • Elective/3
  • Summer Semester (Course/Credit)
    • Research (complete research prospectus)/3

Year of Program 3

  • Fall Semester (Course/Credit)
    • Research/2
    • Elective/3
  • Spring Semester (Course/Credit)
    • Research/2
  • Summer Semester (Course/Credit)
    • Research/2

Formal Presentation of Research at Peer-reviewed Scientific Meetings:
The fellow will attend PPAG each year and additional specialty meetings as appropriate. The fellow will present at least one abstract of their research at PPAG, and will have the opportunity to present at additional professional meetings including the American College of Clinical Pharmacy (ACCP) or Society of Critical Care Medicine (SCCM). The fellow will be responsible for designing the poster (or slides), and preparing the scientific materials that appear in abstract and posters.



Scholarship

The fellow will participate in the peer-review of at least 1-2 manuscripts submitted for publication each year. The fellow will also be expected to contribute to the literature through preparation and publication of newsletter articles, book chapters, case reports, review article, and their original research manuscripts.



Professional Service

Professional Organization Involvement

  • Fellow involvement in local and national professional organizations (as their residency schedule allows) is encouraged. Examples include:
    • Oklahoma Society of Health-System Pharmacists (OSHP)
    • American Society of Health-System Pharmacists (ASHP)
    • American College of Clinical Pharmacy (ACCP)
    • American Association of Colleges of Pharmacy (AACP)
    • Pediatric Pharmacy Advocacy Group (PPAG)
    • University of Oklahoma College of Pharmacy Committees

University of Oklahoma College of Pharmacy Committees

  • Fellow involvement in college committees is also encouraged. Examples include:
    • One academic committee to support the College
    • OUCOP department meetings
    • Other meetings based on fellow interests



Benefits

The fellow is offered a flexible benefits package including medical and dental insurance, 12 paid vacation days per year, paid holidays, and paid interview leave. 



Qualifications

  • Doctor of Pharmacy degree from an ACPE accredited College of Pharmacy
  • Completed a PGY1 pharmacy residency or equivalent experience
  • Eligible for licensure in the state of Oklahoma


Program Director

Peter N. Johnson, Pharm.D., BCPS, BCPPS, FPPAG
Associate Professor, Department of Pharmacy:  Clinical and Administrative Sciences, Oklahoma City, Oklahoma.  Practice area: Pediatric critical care, pediatric pain management, inpatient general pediatrics



Associate Program Director

Sukyung Woo, Ph.D.
Assistant Professor, University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma.  Research area:  Preclinical and clinical pharmacokinetic and pharmacodynamic analysis, pharmacogenomics, PK/PD modeling and simulation, systems pharmacology modeling, protein therapeutics, antiangiogenic therapeutics



Preceptors:

Molly Adams, Pharm.D., Pediatric Clinical Pharmacist, The Children’s Hospital at OU Medical Center, Oklahoma City, OK.  Practice area: Obstetrics/gynecology, neonatology

Jennifer Dannelley, Pharm.D., Pediatric Clinical Pharmacist, University of Oklahoma College of Medicine, Oklahoma City, OK.  Practice area: Cystic fibrosis, pulmonology

Teresa V. Lewis, Pharm.D., BCPS, Assistant Professor, Department of Pharmacy, Clinical and Administrative Sciences, Oklahoma City, OK. Practice area: Pediatric nephrology, pediatric solid organ transplant, general pediatrics

Jamie Miller, Pharm.D., BCPS, BCPPS, Associate Professor, Department of Pharmacy, Clinical and Administrative Sciences, Oklahoma City, OK. Practice area: Neonatology, general pediatrics

Leigh Peek, Pharm.D., BCPS, BCPPS, Pediatric Clinical Pharmacist, The Children’s Hospital at OU Medical Center, Oklahoma City, OK. Practice area: Pediatric inpatient infectious diseases/antimicrobial stewardship, Stem cell transplant, and Pediatric hematology/oncology

Katie Thompson, Pharm.D., BCPS, Clinical Pharmacy Manager, OU Medical System, Oklahoma City, OK. Practice area: Pharmacy practice management

Alana Zuelsdorf, Pharm.D., Pharmacy Operations Manager, The Children’s Hospital at OU Medical Center, Oklahoma City, OK. Practice area: Pharmacy practice management



Current Fellow

Sin Yin (Sean) Lim, Pharm.D., (2017-2020), University of Oklahoma College of Pharmacy, Oklahoma City, OK. PGY1 Pharmacy Residency—University of Oklahoma College of Pharmacy and OU Medical System, Oklahoma City, OK