Vibhudutta Awasthi, Ph.D.

Professor and Associate Dean for Research

Pharmaceutical Sciences

Phone (405) 271-6593 x47331

Fax (405) -271-7505

Office CPB 309

Email vibhudutta-awasthi@ouhsc.edu


Summary


My research interests are in the development of radiopharmaceuticals, small animal imaging and use of radiological imaging techniques to answer physiological questions. My current research focuses on the development of liposome encapsulated hemoglobin as an artificial oxygen carrier and he is studying cerebral oxygen metabolism using positron emission tomography. I am a board certified nuclear pharmacist with expertise in areas related to drug delivery, formulation development, nuclear pharmacy and small animal nuclear imaging.



Publications & Presentations

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    16. Awasthi S, Rahman N, Hedrick A, Awasthi V, Breshears M, Kosanke S. Analysis of health and lung injury markers in mice treated with TLR4-interacting SPA4 peptide. Journal of Immunology (Annual Meeting Abstracts). 2019; 202 : 64.26

    17. Mdzinarishvili A, Houson H, Sidorov E, Awasthi V. Detection of Cerebral Necrosis in Ischemic Stroke Using a New Infarct-Avid Agent 18F-Fluorodeoxyglucaric Acid (FGA) in a Mouse Model of Stroke. BRAIN INJURY. 2019; 33 : 215-215

    18. Awasthi V, Awwad H O, Houson H, Hedrick A, Mdzinarishvili A, Standifer K. Hemorrhagic Shock Aggravates Traumatic Brain Injury: Evidence from PET Imaging Using 18F-Fluorodeoxyglucaric Acid in a Rat Model. BRAIN INJURY. 2019; 33 : 117-118

    19. Virani N, Hedrick A, Wu D, Southard B, Liu H, Awasthi V, Harrison R. Enhanced computed tomography imaging of breast cancer via phosphatidylserine targeted gold nanoparticles. Biomedical Physics & Engineering Express. 2019; 5 : 065019

    20. Mare R, Fresta M, Cosco D, Awasthi V. Anchoring Property of a Novel Hydrophilic Lipopolymer, HDAS-SHP, Post-Inserted in Preformed Liposomes. Nanomaterials. 2019; 9 : 1185

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Grants

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    1. Developing PPARĪ³ acetylation inhibitor for the treatment of aging-related conditions. NIH. Start Date: 2021. End Date: 2026.

    2. Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment. NIH. Start Date: 2021. End Date: 2026.

    3. SBIR Phase I: Early-Stage Development of GPPD for Fatty Liver. NIH.

    4. Surfactant protein-A regions as TLR4-immunomodulators. NIH. Start Date: 2017. End Date: 2023.

    5. STTR Phase I: Cardiotropic Atorvastatin Liposomes for Myocardial Reperfusion Injury. NSF. Start Date: 2023. End Date: 2021.

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Awards and Honors

                                                                                            1. USPTO. Patent application issued. Date: 2015.  

                                                                                            2. Journal of Pharmaceutical Sciences. Article selected as a featured research paper. Date: 2015.  

                                                                                            3. Robert Glenn Rapp Foundation. Presidential Professor . Date: 2013.  

                                                                                            4. Sandra K and David L Gilliland Chair in Nuclear Pharmacy . Date: 2012.  




Education

                                                                                            1.  Degree: Ph D. Sanjay Gandhi Postgraduate Institute of Medical Sciences . Date: 1994.  

                                                                                            2.  Degree: M. Pharm.. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1990.  

                                                                                            3.  Degree: B. Pharm. Dr. Hari Singh Gour Vishwavidyalaya, Sagar (Formerly, University of Sagar). Date: 1988.  




Administrative Assignments

                                                

    1. Role: Associate Dean. Scope: College. Description: Lead research enterprise of the College of Pharmacy. Represent the College at the HSC level. Mentor researchers. Date: 2020.

                                                

    2. Role: Director. Scope: University. Description: Direction and conduct of nuclear imaging services for biomedical investigators; Production of PET radiotracers for preclinical imaging and preparation for regulatory compliance for clinical applications; Consultations with researchers about imaging and tracer applications. Date: 2007.




External Connections and Partnerships


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