Yong Zhang, Ph.D.

Research Associate

Department of Pharmaceutical Sciences

Phone (405) 271-6593 x47234

Fax (405) 271-7505

Office CPB 259

Email yong-zhang@ouhsc.edu


Publications & Presentations

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  1. Awwad H O, Durand C D, Gonzalez L P, Tompkins P, Zhang Y, Lerner M R, Brackett D J, Sherry D M, Awasthi V, Standifer K. Post-blast treatment with Nociceptin/Orphanin FQ peptide (NOP) receptor antagonist reduces brain injury-induced hypoxia and signaling proteins in vestibulomotor-related brain regions. Behavioural brain research. 2018
  2. Mohammed A, Janakiram N B, Madka V, Pathuri G, Li Q, Ritchie R, Biddick L, Kutche H, Zhang Y, Singh A, Gali H, Lightfoot S, Steele V E, Suen C S, Rao C V. Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer. Oncotarget. 2017; 8 : 97822-97834
  3. Zhang Y, Simpson-Durand C D, Standifer K. Nociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorder. British journal of pharmacology. 2015; 172 : 571-82
  4. Awwad H O, Simpson-Durand C D, Gonzalez L P, Tompkins P, Zhang Y, Lerner M, Brackett D J, Sherry D M, Awasthi V, Standifer K. Post-blast treatment with Nociceptin/Orphanin FQ peptide receptor antagonist reduces traumatic brain injury-induced cerebral hypoxia. Neuroscience 2014 program and website. 2014
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Grants

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  • Post-traumatic stress disorder and co-morbid chronic pain: evidence that TNF initiates a sequelae involving Nociceptin/OFQ. 2017.
  • Time-dependent treatment: Early blockade of TNF prevents development of PTSD and co-morbid allodynia. 2018.
  • Modulation of Immune Responses by N/OFQ-NOP Receptor System In PTSD. 2014.
  • Modulation of Inflammatory Mechanisms Underlying Chronic Pain of Posttraumatic Stress Disorder: Prevention and Treatment. 2015.
  • Diabetic neuropathic pain in posttraumatic stress disorder: Role of Nociceptin/Orphanin FQ. 2015.
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