Michael McShan , Ph.D.
Associate Professor of Pharmaceutical Sciences
Department of Pharmaceutical Sciences
Education & Experience
Education
Baylor University, BM, 1976
Baylor College of Medicine, Ph.D. Microbiology and Immunology, 1988
Selected Publications & Presentations
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Suvorov AN, McShan WM, Ferretti JJ. Bacteriophage content of M49 strains of Streptococcus pyogenes. FEMS Microbiology Letters 2009; 294:9-15.
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Scott J, Thompson-Mayberry P, Lahmamsi S, King CJ, McShan WM. Phage-associated mutator phenotype in group A streptococcus. J Bacteriol 2008; 190(19): 6290-6301.
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McShan WM, Ferretti JJ, Karasawa T, Suvorov AN, Lin S, Qin B, Jia H, Kenton S, Najar F, Wu H, Scott J, Roe BA, Savic DJ. Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes. J Bacteriol 2008; 190(23): 7773-7785.
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Malke H, Steiner K, McShan WM, Ferretti JJ. Linking the nutritional status of Streptococcus pyogenes to alteration of transcriptional gene expression: The action of CodY and ReIA. Intl J Medical Microbiology 2006; 296:259-275.
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McShan WM, Savid DJ. The timing of streptolysin O release is controlled by the sloR operon. Intl Congress Series 2006; 1289:199-202.
Current Grants Awarded
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NIH - The streptolysin regulator (sloR) of streptococcus pyogenes.
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NIH - Bacteriophage control of DNA repair in Streptococcus pyogenes
Completed Grants
- 9/1/2007 -8/31/2008 American Foundation for Pharmaceutical Education (AFPE) - Contribution of mismatch repair (MMR) converting prophages to the host phenotype in group A Streptococci (Fellowship)
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8/1/2006 - 7/31/2007 Oklahoma Center for the Advancement of Science and Technology (OCAST) - Gene expression in wild-type and resistant Pneumococci
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1/1/2004 - 12/31/2006 American Heart Association (AHA) - The streptolysin regulator of Strepococcus pygenes