People

Lucila  Garcia-Contreras , Ph.D.

Assistant Professor

Department of Pharmaceutical Sciences

Phone (405) 271-6593  x47205
Fax (405) 271-7505
Office   CPB 321
Email lucila-garcia-contreras@ouhsc.edu

Research Summary

The main interest of our laboratory is the targeted delivery of drugs and primarily Pulmonary Drug Delivery. Our goal is to design therapies that are more efficient and more convenient in delivering therapeutic or prophylactic agents to the site of action, thereby maximizing efficacy and efficiency of the agent and minimizing its undesired side effects.
 
My research objectives are encompassed in the following four areas:
  1. To study mechanisms of drug transport in the lung in order to maximize delivery strategies;
  2. To optimize currently proposed therapies for the treatment of pulmonary diseases such as tuberculosis and cystic fibrosis;
  3. To understand the mechanisms of immunogenicity and protection when vaccines are administered by the pulmonary route; and
  4. To design more effective therapies for the treatment of lung cancer.

Education & Experience

Education
  • Postdoctoral Fellowship, 2003. Division of Drug Delivery and Disposition, School of Pharmacy. Univ. of North Carolina at Chapel Hill. Chapel Hill, NC. 
  • Doctor of Philosophy, 1999. Dept. of Pharmaceutical and Biomedical Sciences, College of Pharmacy, Univ. of Georgia. Athens, GA.
  • Master of Science, 1995. Dept. of Pharmaceutics, College of Pharmacy, Univ. of Georgia. Athens, GA.

Experience

  • Assistant Professor, Dept. of Pharmaceutical Sciences, Univ. of Oklahoma College of Pharmacy, OKC, OK. 2011-present.
  • Research Associate Professor, Division of Drug Delivery and Disposition, School of Pharmacy, Univ. of North Carolina at Chapel Hill, NC. 2008-2010
  • Research Assistant Professor, Division of Drug Delivery and Disposition, School of Pharmacy, Univ. of North Carolina at Chapel Hill, NC. 2004-2008.
  • Post-Doctoral Research Associate, Division of Drug Delivery and Disposition, School of Pharmacy, Univ. of North Carolina at Chapel Hill, NC.

Honors & Service

Honors
  • Best poster presentation, 2nd session. "Effect of food on the chronokinetics of ampicillin." Graduate Research Association of Students in Pharmaceutics meeting. Univ. of Florida. 1997.
  • Fulbright-Conacyt Scholarship recipient. 1993-1999.
  • Graduate assistantship recipient, Univ. of Georgia. 1994-1999.
  • Gabino Barreda Medal-UNAM. Given to the student with the highest GPA of the 1990 class of pharmacists. FES Cuautitian UNAM, Mexico.

Professional Activities and Positions

  • Consultant for BioSante Pharmaceuticals (Doylston, PA), Momenta Pharmaceuticals (Boston, MA) and Parion Sciences (RTP, Durham, NC).
  • Grant Reviewer for NIH's Delivery Systems and Nanotechnology study section and the extramural program review for NIDA
  • Journal Reviewer for the following peer-reviewed journals: Journal of Aerosols in Medicine, Journal of Pharmaceutical Sciences, AAPS PharmSci Tech, Biopharmaceuticals and Drug Disposition, Journal of Gene Medicine, Intl Journal of Tuberculosis and Lung Disease, Journal of Antimicrobial Agents, Drug Development and Industrial Pharmacy, European Journal of Pharmaceutics and Biopharmaceutics, Expert Review of Vaccines.
view full profile

Selected Publications & Presentations

  1. Ibrahim M, Garcia-Contreras L. Preclinical Pharmacokinetics of Antitubercular Drugs John Wiley & Sons, Ltd.. 2016; pages 131-155, total number of pages 425.
  2. Hatipoglu S M, Mahjabeen S, Benbrook D M, Garcia-Contreras L. Development and Validation of Reverse Phase HPLC Method for SHetA2 in Gynecological Tissue for Treatment of Cervical Dysplasia American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. 2016;
  3. Ibrahim M, Hatipoglu S M, Benbrook D M, Garcia-Contreras L. Dissolution Studies for Inhalable Sheta2 Dry Powder Using a Novel Flow-Through Cell Apparatus American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. 2016;
  4. Mahjabeen S, Chandra V, Hatipoglu S M, Benbrook D M, Garcia-Contreras L. Formulation of SHetA2 in a Vaginal Suppository for Chemoprevention Against Cervical Dysplasia American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. 2016;
  5. Ibrahim M, Benbrook D M, Garcia-Contreras L. In Vitro Uptake of Inhalable SHetA2 Microparticles by RAW Macrophages and Their Efficacy against Intracellular Mycobacterium Tuberculosis American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. 2016;
  6. show more